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          Harrison's Principles of Internal Medicine, Twenty-First Edition (Vol.1 & Vol.2) 21st Edition (IE)
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          출판사 McGraw-Hill
          저자 Joseph Loscalzo,Anthony S. Fauci,Dennis L. Kasper,Stephen L. Hauser,Dan L. Longo,J. Larry Jameson
          발행일 2022-04-15
          ISBN 9781264285846
          판형 Hardcover | 21판
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          The Voice of Clinical Reason

          Harrison’s Principles of Internal Medicine is the world's most trusted clinical medicine text―and a superb resource for learning the art and science of clinical reasoning. Recognized by healthcare professionals worldwide as the leading authority on applied pathophysiology and clinical medicine, Harrison’s Principles of Internal Medicine provides the informational foundation you need for the best patient care possible. This new edition is fully updated with timely new chapters and essential updates across the spectrum of internal medicine. 

          Written and edited by the world’s top experts in their respective fields, this landmark guide provides comprehensive, accurate, and essential coverage of the pathogenesis, diagnosis, and treatment of disease. 

          Harrison’s is world-renowned as the most authoritative source for: 

           Clear, concise schemas that facilitate the generation of differential diagnoses to reason efficiently through complex real world clinical cases
          • The physiologic and epidemiologic basis of signs and symptoms, which are covered through a wealth of unsurpassed expert guidance and linked to the disease-specific chapters that follow
          • Updated clinical trial results and recommended guidelines
          • Excellent and extensive visual support, including radiographs, clinical photos, schematics, and high-quality drawings
          • Coverage of both therapeutic approaches and specific treatment regimens
          • Practical clinical decision trees and algorithms
          • Organ/system-specific sections, with clinically relevant pathophysiology and practical clinical advice on the approach to the patient, strategies towards building a differential diagnosis, outstanding clinical algorithms and diagnostic schema, a wealth of clinical images and diagrams, current clinical guidelines, and general and specific approaches to therapy

          Harrison’s remains the most trusted resource in a world influenced by endless sources of medical information. The most timely and comprehensive updates from the world’s top experts are featured in the 21st edition: 

           Current coverage of the diagnosis and treatment of diseases, from COVID to dementia to sepsis to multiple sclerosis to lung cancer
          • Updated content that reflects new approved therapeutics and new practice-changing guidelines and evidence summaries
          • More than 1000 clinical, pathological, and radiographic photographs, diagnostic and therapeutic decision trees, and clear schematics and diagrams describing pathophysiologic processes
          • Numerous atlases featuring curated collections of important visual aspects of diagnosis and management
          • Updated and time-saving curation and synthesis of established and new medical literature and studies
          • Clinically relevant coverage of disease mechanics and pathophysiology, and related therapeutic mechanisms



          Part 1: The Profession of Medicine
          Updated! Chapter 1: The Practice of Medicine
          Updated! Chapter 2: Promoting Good Health
          Updated! Chapter 3: Vaccine Opposition and Hesitancy
          Updated! Chapter 4: Decision-Making in Clinical Medicine
          Updated! Chapter 5: Precision Medicine and Clinical Care
          New! Chapter 6: Screening and Prevention of Disease
          Updated! Chapter 7: Global Diversity of Health System Financing and Delivery
          Updated! Chapter 8: The Safety and Quality of Health Care
          Updated! Chapter 9: Diagnosis: Reducing Errors and Improving Quality
          New! Chapter 10: Racial and Ethnic Disparities in Health Care
          Updated! Chapter 11: Ethical Issues in Clinical Medicine
          New! Chapter 12: Palliative and End-of-Life Care
          Part 2: Cardinal Manifestations and Presentation of Diseases
          Section 1: Pain
          New! Chapter 13: Pain: Pathophysiology and Management
          New! Chapter 14: Chest Discomfort
          New! Chapter 15: Abdominal Pain
          New! Chapter 16: Headache
          New! Chapter 17: Back and Neck Pain
          Section 2: Fever
          New! Chapter 18: Fever
          New! Chapter 19: Fever and Rash
          New! Chapter 20: Fever of Unknown Origin
          Section 3: Nervous System Dysfunction
          New! Chapter 21: Syncope
          Updated! Chapter 22: Dizziness and Vertigo
          New! Chapter 23: Fatigue
          New! Chapter 24: Neurologic Causes of Weakness and Paralysis
          New! Chapter 25: Numbness, Tingling, and Sensory Loss
          New! Chapter 26: Gait Disorders, Imbalance, and Falls
          Updated! Chapter 27: Confusion and Delirium
          New! Chapter 28: Coma
          New! Chapter 29: Dementia
          New! Chapter 30: Aphasia, Memory Loss, and Other Cognitive Disorders
          New! Chapter 31: Sleep Disorders
          Section 4: Disorders of Eyes, Ears, Nose, and Throat
          New! Chapter 32: Disorders of the Eye
          New! Chapter 33: Disorders of Smell and Taste
          New! Chapter 34: Disorders of Hearing
          New! Chapter 35: Upper Respiratory Symptoms, Including Earache, Sinus Symptoms, and Sore Throat
          New! Chapter 36: Oral Manifestations of Disease
          Section 5: Alterations in Circulatory and Respiratory Functions
          New! Chapter 37: Dyspnea
          New! Chapter 39: Hemoptysis
          New! Chapter 38: Cough
          New! Chapter 40: Hypoxia and Cyanosis
          New! Chapter 41: Edema
          New! Chapter 43: Palpitations
          Section 6: Alterations in Gastrointestinal Function
          New! Chapter 44: Dysphagia
          New! Chapter 45: Nausea, Vomiting, and Indigestion
          New! Chapter 46: Diarrhea and Constipation
          New! Chapter 47: Unintentional Weight Loss
          Updated! Chapter 48: Gastrointestinal Bleeding
          New! Chapter 49: Jaundice
          Updated! Chapter 50: Abdominal Swelling and Ascites
          Section 7: Alterations in Renal and Urinary Tract Function
          New! Chapter 51: Interstitial Cystitis/Bladder Pain Syndrome
          New! Chapter 52: Azotemia and Urinary Abnormalities
          New! Chapter 54: Hypercalcemia and Hypocalcemia
          New! Chapter 55: Acidosis and Alkalosis
          Section 8: Alterations in the Skin
          New! Chapter 56: Approach to the Patient with a Skin Disorder
          New! Chapter 57: Eczema, Psoriasis, Cutaneous Infections, Acne, and Other Common Skin Disorders
          New! Chapter 58: Skin Manifestations of Internal Disease
          New! Chapter 59: Immunologically Mediated Skin Diseases
          New! Chapter 60: Cutaneous Drug Reactions
          New! Chapter 61: Photosensitivity and Other Reactions to Sunlight
          Section 9: Hematologic Alterations
          New! Chapter 62: Interpreting Peripheral Blood Smears
          New! Chapter 63: Anemia and Polycythemia
          New! Chapter 64: Disorders of Granulocytes and Monocytes
          New! Chapter 65: Bleeding and Thrombosis
          New! Chapter 66: Enlargement of Lymph Nodes and Spleen
          Part 3: Pharmacology
          New! Chapter 67: Principles of Clinical Pharmacology
          Updated! Chapter 68: Pharmacogenomics
          Part 4: Oncology and Hematology
          Section 1: Neoplastic Disorders
          New! Chapter 70: Prevention and Early Detection of Cancer
          New! Chapter 71: Cancer Genetics
          New! Chapter 72: Cancer Cell Biology
          New! Chapter 73: Principles of Cancer Treatment
          New! Chapter 75: Oncologic Emergencies
          New! Chapter 76: Cancer of the Skin
          New! Chapter 77: Head and Neck Cancer
          New! Chapter 80: Upper Gastrointestinal Tract Cancers
          New! Chapter 81: Lower Gastrointestinal Cancers
          New! Chapter 82: Tumors of the Liver and Biliary Tree
          New! Chapter 85: Renal Cell Carcinoma
          New! Chapter 86: Cancer of the Bladder and Urinary Tract
          New! Chapter 87: Benign and Malignant Diseases of the Prostate
          New! Chapter 88: Testicular Cancer
          New! Chapter 89: Gynecologic Malignancies
          New! Chapter 90: Primary and Metastatic Tumors of the Nervous System
          New! Chapter 91: Soft Tissue and Bone Sarcomas and Bone Metastases
          New! Chapter 93: Paraneoplastic Syndromes: Endocrinologic/Hematologic
          New! Chapter 95: Cancer Survivorship and the Long-Term Impact of Cancer and Its Treatment
          Section 2: Hematopoietic Disorders
          New! Chapter 96: Hematopoietic Stem Cells
          New! Chapter 97: Iron Deficiency and Other Hypoproliferative Anemias
          New! Chapter 99: Megaloblastic Anemias
          New! Chapter 101: Anemia Due to Acute Blood Loss
          New! Chapter 102: Bone Marrow Failure Syndromes Including Aplastic Anemia and Myelodysplasia
          New! Chapter 103: Polycythemia Vera and Other Myeloproliferative Neoplasms
          New! Chapter 105: Chronic Myeloid Leukemia
          New! Chapter 108: Non-Hodgkin’s Lymphoma
          New! Chapter 109: Hodgkin’s Lymphoma
          New! Chapter 112: Amyloidosis
          New! Chapter 113: Transfusion Therapy and Biology
          New! Chapter 114: Hematopoietic Cell Transplantation
          Section 3: Disorders of Hemostasis
          New! Chapter 115: Disorders of Platelets and Vessel Wall
          New! Chapter 118: Antiplatelet, Anticoagulant, and Fibrinolytic Drugs
          Part 5: Infectious Diseases
          Section 2: Clinical Syndromes: Community-Acquired Infections
          New! Chapter 126: Pneumonia
          New! Chapter 138: Acute Meningitis
          New! Chapter 139: Chronic and Recurrent Meningitis
          New! Chapter 140: Brain Abscess and Empyema
          New! Chapter 141: Infectious Complications of Bites
          Section 3: Clinical Syndromes: Health Care-Associated Infections
          New! Chapter 142: Infections Acquired in Health Care Facilities
          New! Chapter 143: Infections in Transplant Recipients
          Section 4: Therapy for Bacterial Diseases
          New! Chapter 144: Treatment and Prophylaxis of Bacterial Infections
          New! Chapter 145: Bacterial Resistance to Antimicrobial Agents
          Section 5: Diseases Caused by Gram-Positive Bacteria
          New! Chapter 146: Pneumococcal Infections
          New! Chapter 147: Staphylococcal Infections
          New! Chapter 148: Streptococcal Infections
          New! Chapter 149: Enterococcal Infections
          New! Chapter 150: Diphtheria and Other Corynebacterial Infections
          New! Chapter 151: Listeria monocytogenes Infections
          New! Chapter 152: Tetanus
          New! Chapter 153: Botulism
          New! Chapter 154: Gas Gangrene and Other Clostridial Infections
          Section 6: Diseases Caused by Gram-Negative Bacteria
          New! Chapter 155: Meningococcal Infections
          New! Chapter 157: Haemophilus and Moraxella Infections
          New! Chapter 158: Infections Due to the HACEK Group and Miscellaneous Gram-Negative Bacteria
          New! Chapter 159: Legionella Infections
          New! Chapter 160: Pertussis and Other Bordetella Infections
          New! Chapter 161: Diseases Caused by Gram-Negative Enteric Bacilli
          New! Chapter 162: Acinetobacter Infections
          Part 7: Disorders of the Respiratory System
          Section 1: Diagnosis of Respiratory Disorders
          New! Chapter 284: Approach to the Patient with Disease of the Respiratory System
          New! Chapter 285: Disturbances of Respiratory Function
          Section 2: Diseases of the Respiratory System
          New! Chapter 288: Hypersensitivity Pneumonitis and Pulmonary Infiltrates with Eosinophilia
          Part 9: Disorders of the Kidney and Urinary Tract
          New! Chapter 309: Cell Biology and Physiology of the Kidney
          New! Chapter 312: Dialysis in the Treatment of Kidney Failure
          New! Chapter 314: Glomerular Diseases
          New! Chapter 315: Polycystic Kidney Disease and Other Inherited Disorders of Tubule Growth and Development
          New! Chapter 317: Vascular Injury to the Kidney
          New! Chapter 318: Nephrolithiasis
          New! Chapter 319: Urinary Tract Obstruction
          New! Chapter 320: Interventional Nephrology
          Part 11: Immune-Mediated, Inflammatory, and Rheumatologic Disorders
          Section 2: Disorders of Immune-Mediated Injury
          New! Chapter 353: Anaphylaxis
          New! Chapter 354: Mastocytosis
          New! Chapter 357: Antiphospholipid Syndrome
          New! Chapter 361: Sjögren’s Syndrome
          New! Chapter 364: Behçet Syndrome
          Part 12: Endocrinology and Metabolism
          Section 1: Endocrinology
          New! Chapter 383: Hypothyroidism
          Part 13: Neurologic Disorders
          Section 2: Diseases of the Central Nervous System
          New! Chapter 431: Alzheimer’s Disease




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